The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.
NCT07397403 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 400
Last updated 2026-02-09
Summary
The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand
Participation in this study will last approximately 12 weeks and will include 2-3 clinic visits, along with 10-11 follow-up phone contacts over a period of 11 weeks.
Conditions
- Syphilis Infection
- Gonorrhea
- Chlamydia
Interventions
- DRUG
-
Doxycycline (200mg/day)
Doxycycline 200 mg single dose after unprotected sex within 24-72 hours
Sponsors & Collaborators
-
Mahidol University
collaborator OTHER -
Bangrak STIs Center
lead OTHER_GOV
Principal Investigators
-
Rossaphorn KITTIYAOWAMARN, MD · Bangrak STIs Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Days
- Max Age
- 60 Days
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-10-06
- Primary Completion
- 2026-10-05
- Completion
- 2027-05-31
Countries
- Thailand
Study Locations
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