The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing STIs Among MSM in Bangkok, Thailand.

NCT07397403 · Status: RECRUITING · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 400

Last updated 2026-02-09

No results posted yet for this study

Summary

The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand

Participation in this study will last approximately 12 weeks and will include 2-3 clinic visits, along with 10-11 follow-up phone contacts over a period of 11 weeks.

Conditions

  • Syphilis Infection
  • Gonorrhea
  • Chlamydia

Interventions

DRUG

Doxycycline (200mg/day)

Doxycycline 200 mg single dose after unprotected sex within 24-72 hours

Sponsors & Collaborators

  • Mahidol University

    collaborator OTHER
  • Bangrak STIs Center

    lead OTHER_GOV

Principal Investigators

  • Rossaphorn KITTIYAOWAMARN, MD · Bangrak STIs Center

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Days
Max Age
60 Days
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-06
Primary Completion
2026-10-05
Completion
2027-05-31

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07397403 on ClinicalTrials.gov