Optimal Treatment of MRSA Throat Carriers
NCT04104178 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 53
Last updated 2025-09-24
Summary
The aim of this study is to investigate the optimal way to treat MRSA throat carriers.
Conditions
- MRSA
- MRSA Colonization
Interventions
- DRUG
-
Clindamycin
Investigating whether a significantly higher number of MRSA throat carriers succeed in becoming MRSA free, when using Clindamycin on top of our general recommended topical treatment of Mupirocin nasal ointment + chorhexidin baths
- DRUG
-
Placebo
Sponsors & Collaborators
-
Hvidovre University Hospital
lead OTHER
Principal Investigators
-
Mona KA Holm, MD · Hvidovre University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-05-20
- Primary Completion
- 2025-09-18
- Completion
- 2025-09-18
Countries
- Denmark
Study Locations
More Related Trials
-
Retapamulin for Reducing MRSA Nasal Carriage
NCT01461668 ·Status: COMPLETED ·Phase: PHASE4
-
Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
NCT00711854 ·Status: COMPLETED ·Phase: PHASE4
-
Study of the Nasal Decolonisation of Staphylococcus Aureus (SA) and the Safety and Tolerability of XF-73 Nasal Gel in Healthy Subjects
NCT02282605 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Whole Body Washing With Chlorhexidine for the Eradication of MRSA
NCT00266448 ·Status: COMPLETED ·Phase: PHASE2
-
MRSA in a Trauma Population: Does Decolonization Prevent Infection?
NCT01820455 ·Status: COMPLETED ·Phase: NA
-
A Prospective Trial of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Methicillin Resistant Staphylococcus Aureus Infections
NCT01049438 ·Status: COMPLETED ·Phase: NA
-
Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Participants With Staphylococcus Aureus Bacteremia Receiving Standard-of-Care (SOC) Antibiotics
NCT03162250 ·Status: COMPLETED ·Phase: PHASE1
-
Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus
NCT00730028 ·Status: COMPLETED ·Phase: PHASE2
-
Comprehensive Strategy to Decolonize Methicillin-resistant Staphylococcus Aureus (MRSA) in the Outpatient Setting
NCT01232231 ·Status: COMPLETED ·Phase: NA
-
Azithromycin for Meningococcal Carriage
NCT06618534 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy Study of Altabax to Clear Methicillin-resistant Staphylococcus Aureus (MRSA) Nasal Colonization
NCT00856089 ·Status: WITHDRAWN ·Phase: PHASE4
-
Evaluation of the Efficacy of Bio-K+ Cl-1285® In the Nasal Decolonization of Methicillin Resistant Staphylococcus Aureus (MRSA) Carrier Patients
NCT00941356 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia
NCT05184764 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"
NCT00729937 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Novel Approach to Methicillin-resistant Staphylococcus Aureus (MRSA) Screening of Colonized Patients
NCT01234831 ·Status: COMPLETED ·Phase: NA
-
Clinical Evaluation of the Residual Antimicrobial Activity
NCT04495920 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant/-Sensitive Staphylococcus Aureus (MRSA/MSSA)
NCT01158235 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Methicillin-resistant Staphylococcus Aureus (MRSA) Skin and Soft Tissue Infection (SSTI) Prevention in Military Trainees
NCT01105767 ·Status: COMPLETED ·Phase: NA
-
Mycoplasma Genitalium Antibiotic Susceptibility and Treatment (MEGA)
NCT00358462 ·Status: COMPLETED ·Phase: PHASE3
-
Effectiveness of Antibiotic Delivery Via Bio-absorbable Sponge
NCT01222832 ·Status: COMPLETED ·Phase: PHASE2
-
Nosocomial Pneumonia With Suspected Or Proven Methicillin-Resistant Staphylococcus Aureus (MRSA)
NCT00084266 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy Study of Vitamin D Supplementation to Meticillin Resistant Staphylococcus Aureus (MRSA) Carriers
NCT02178488 ·Status: COMPLETED ·Phase: PHASE2
-
NAsal MEthicillin-resistant Staphylococcus (NAMES): a Prospective Study to Assess the Impact of Antibiotic Therapy on Nasal Colonization with Methicillin-resistant Staphylococcus Aureus (MRSA) Inhospitalized Children
NCT06872099 ·Status: RECRUITING
-
Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant
NCT05695196 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study to Evaluate the Safety and Efficacy of 3% LTX-109 for Nasal Decolonisation of Staphylococcus
NCT04767321 ·Status: COMPLETED ·Phase: PHASE1/PHASE2