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Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy

NCT07393711 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 95

Last updated 2026-02-11

No results posted yet for this study

Summary

Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL). Bacterial colonization and persistent infection are recognized contributors to stone recurrence.

This study evaluates the effectiveness of intrarenal dioxidine instillation as a metaphylactic measure to reduce recurrence of infection-related kidney stones following PCNL. Patients undergoing PCNL will receive standard treatment, with or without adjunctive intrarenal dioxidine administration. The study aims to assess whether this approach reduces stone recurrence and infection-related complications.

Conditions

Interventions

DRUG

Dioxidine

Intrarenal instillation of dioxidine solution after PCNL to reduce bacterial colonization and prevent recurrence of infection-related stones.

PROCEDURE

Percutaneous Nephrolithotripsy (PCNL)

Standard percutaneous nephrolithotripsy procedure for removal of kidney stones.

Sponsors & Collaborators

  • West Kazakhstan Marat Ospanov Medical University

    lead OTHER

Principal Investigators

  • Bazylbek S Zhakiev, MD · West Kazakhstan Marat Ospanov Medical University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-03-01
Primary Completion
2026-06-30
Completion
2026-12-30

Countries

  • Kazakhstan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07393711 on ClinicalTrials.gov