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Molecular Determinants of Spinal Cord Injury Rehabilitation

NCT07383077 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 106

Last updated 2026-02-03

No results posted yet for this study

Summary

This study main aim is to identify molecular determinants of better recovery following spinal cord injury (SCI), as biomarkers of neurological and/or functional improvement and a proxy for neuroregeneration. For that, omics analyses of several biological samples will be performed, to comprehensively portray the molecular and cellular profiles of the patients with SCI at key time points of the pathology: pre-rehabilitation, post-rehabilitation and one-year post-injury. The main question it aims to answer is: 'Are there specific molecules (and related biological pathways) that impact the functional recovery of spinal cord injury patients during the subacute phase, in a way that future targeted pharmacological or genetic interventions may improve SCI outcomes?'.

Conditions

  • Spinal Cord Injury

Sponsors & Collaborators

  • Aveiro Institute of Biomedicine (iBiMED)

    collaborator UNKNOWN

  • Department of Medical Sciences, University of Aveiro

    collaborator UNKNOWN

  • Centro de Reabilitacao do Norte

    collaborator OTHER

  • Unidade Local de Saude de Gaia e Espinho EPE

    collaborator OTHER

  • Centro Academico Clínico Egas Moniz Health Alliance

    collaborator OTHER

  • Prof. Sandra Vieira

    lead OTHER

Principal Investigators

  • Sandra I. Vieira, Prof. Dr. · Institute of Biomedicine, Department of Medical Sciences, University of Aveiro (iBiMED-UA)

  • Maria Ribeiro da Cunha, MD · Centro de Reabilitação do Norte (CRN)/Unidade Local de Saúde de Gaia e Espinho, E.P.E. (ULSGE)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-05-01
Primary Completion
2023-10-16
Completion
2023-10-16

Countries

  • Portugal

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07383077 on ClinicalTrials.gov