Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

NCT06023186 ·Status: RECRUITING

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

NCT06947590 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

NCT04349072 ·Status: COMPLETED ·Phase: PHASE3

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

NCT07168655 ·Status: COMPLETED

The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular Obstruction

NCT07103655 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4

A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada

NCT06549608 ·Status: ACTIVE_NOT_RECRUITING

Real-World Effectiveness of Mavacamten in Canada

NCT06338202 ·Status: COMPLETED

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

NCT05489705 ·Status: RECRUITING

A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

NCT03442764 ·Status: COMPLETED ·Phase: PHASE2

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT03470545 ·Status: COMPLETED ·Phase: PHASE3

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

NCT07004972 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

NCT05135871 ·Status: COMPLETED ·Phase: PHASE1

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

NCT03496168 ·Status: COMPLETED ·Phase: PHASE2

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

NCT06372457 ·Status: ACTIVE_NOT_RECRUITING

A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT07023341 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

Precision Pharmacogenetics and Genotype Class Based Prediction of Mavacamten Response in Obstructive Hypertrophic Cardiomyopathy

NCT07408427 ·Status: NOT_YET_RECRUITING

Ademetionine in Obstructive Hypertrophic Cardiomyopathy

NCT07367724 ·Status: RECRUITING ·Phase: PHASE2

Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial

NCT07120776 ·Status: RECRUITING ·Phase: NA

The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy

NCT04706429 ·Status: COMPLETED ·Phase: PHASE2

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

NCT06551129 ·Status: RECRUITING

Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection Fraction

NCT02695420 ·Status: COMPLETED ·Phase: PHASE2

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

NCT04766892 ·Status: COMPLETED ·Phase: PHASE2

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

NCT06081894 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy

NCT07021976 ·Status: RECRUITING ·Phase: PHASE3

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

NCT04219826 ·Status: COMPLETED ·Phase: PHASE2