Mavacamten in Obstructive Hypertrophic Cardiomyopathy

A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)

NCT03442764 ·Status: COMPLETED ·Phase: PHASE2

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT06253221 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

A Retrospective Cohort Study of Mavacamten Patient Support Program in Canada

NCT06549608 ·Status: ACTIVE_NOT_RECRUITING

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT03470545 ·Status: COMPLETED ·Phase: PHASE3

Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic Cardiomyopathy

NCT06947590 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA

A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy

NCT04349072 ·Status: COMPLETED ·Phase: PHASE3

A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy

NCT05414175 ·Status: COMPLETED ·Phase: PHASE3

Real-World Effectiveness of Mavacamten in Canada

NCT06338202 ·Status: COMPLETED

Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEER

NCT03496168 ·Status: COMPLETED ·Phase: PHASE2

Real-world Patient Reported Outcomes Among Patients Treated With Camzyos

NCT06551129 ·Status: RECRUITING

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

NCT07004972 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

NCT04766892 ·Status: COMPLETED ·Phase: PHASE2

COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)

NCT06372457 ·Status: ACTIVE_NOT_RECRUITING

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

NCT05135871 ·Status: COMPLETED ·Phase: PHASE1

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

NCT07210723 ·Status: RECRUITING ·Phase: PHASE2/PHASE3

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

NCT06081894 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

NCT04164732 ·Status: COMPLETED ·Phase: PHASE2

Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart Failure

NCT03759392 ·Status: COMPLETED ·Phase: PHASE3

A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT07023341 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

NCT06736574 ·Status: RECRUITING ·Phase: PHASE3

Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH Trial

NCT07120776 ·Status: RECRUITING ·Phase: NA

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

NCT02842242 ·Status: COMPLETED ·Phase: PHASE2

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

NCT06412666 ·Status: RECRUITING ·Phase: PHASE2/PHASE3

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

NCT03153111 ·Status: COMPLETED ·Phase: PHASE2

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects

NCT03153137 ·Status: COMPLETED ·Phase: PHASE3