A Phase III Trial of HRS-1893 in Patients With Obstructive Hypertrophic Cardiomyopathy

Study on the Efficacy and Safety of HRS-7535 in Patients With Mild Decrease in Ejection Fraction/Preserved Ejection Fraction Heart Failure and Obesity

NCT06820099 ·Status: RECRUITING ·Phase: PHASE2

Study of Efficacy of Oral Sacubitril/Valsartan in Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

NCT04164732 ·Status: COMPLETED ·Phase: PHASE2

A Trial of HRS-1893 in Healthy Volunteers

NCT07033455 ·Status: COMPLETED ·Phase: EARLY_PHASE1

HRS9531 Injection in Obese Subjects With Heart Failure With Preserved Ejection Fraction

NCT06391710 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial

NCT04826185 ·Status: COMPLETED ·Phase: PHASE2

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM

NCT06081894 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

Efficacy, Safety, and Tolerability of Perhexiline in Subjects With Hypertrophic Cardiomyopathy and Heart Failure

NCT02431221 ·Status: WITHDRAWN ·Phase: PHASE3

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

NCT05767346 ·Status: COMPLETED ·Phase: PHASE3

Phase II Clinical Study of HRS-9057 Injection in Patients With Heart Failure-induced Fluid Retention

NCT07318103 ·Status: RECRUITING ·Phase: PHASE2

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

NCT04219826 ·Status: COMPLETED ·Phase: PHASE2

Heart Function and Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

NCT00354328 ·Status: COMPLETED

A Study of HRS-5632 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

NCT07185776 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy

NCT05582395 ·Status: COMPLETED ·Phase: PHASE3

A Study of Mavacamten in Obstructive Hypertrophic Cardiomyopathy

NCT05414175 ·Status: COMPLETED ·Phase: PHASE3

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

NCT06116968 ·Status: COMPLETED ·Phase: PHASE3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

NCT05714085 ·Status: RECRUITING ·Phase: PHASE2/PHASE3

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM

NCT05186818 ·Status: COMPLETED ·Phase: PHASE3

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

NCT07023614 ·Status: RECRUITING ·Phase: PHASE2

A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

NCT07023341 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3

The Efficacy and Mechanism of Trientine in Patients With Hypertrophic Cardiomyopathy

NCT04706429 ·Status: COMPLETED ·Phase: PHASE2

A Safety, Tolerability, Pharmacokinetic Study of SHR-6934 Injection in Healthy Subjects

NCT06700083 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1

Evaluate Efficacy, Safety and Tolerability of JTT-861 in Subjects With Heart Failure With Reduced Ejection Fraction

NCT06017609 ·Status: COMPLETED ·Phase: PHASE2

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

NCT02862600 ·Status: TERMINATED ·Phase: PHASE2

Randomized, Double-Blind, Placebo-Controlled, Safety and Tolerability Study of ITI-214 in Patients With Heart Failure

NCT03387215 ·Status: COMPLETED ·Phase: PHASE1/PHASE2

A Research Study on the Effects of NNC0537-1482 in Participants With Heart Failure

NCT07218627 ·Status: RECRUITING ·Phase: PHASE1