Thermal Radiofrequency Neurolysis Versus Alcoholic Neurolysis of the Genicular Nerves for Treatment of Chronic Knee Pain in Advanced Knee Osteoarthritis
NCT07125768 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2025-08-15
Summary
This study aimed to compare the strength and duration of pain relief, quality of life and analgesic consumption between patients who undergo conventional thermal radiofrequency vs patients who undergo chemical neurolysis on genicular nerves by alcohol in chronic knee osteoarthritis pain.
Conditions
- Thermal Radiofrequency Neurolysis
- Alcoholic Neurolysis
- Genicular Nerves
- Treatment
- Chronic Knee Pain
- Advanced Knee Osteoarthritis
Interventions
- OTHER
-
Thermal Radiofrequency Neurolysis
Patients received C-arm guided neurolysis of superior medial \[SM\], superior lateral \[SL\], and inferior medial \[IM\] genicular nerves by thermal radiofrequency.
- OTHER
-
Alcoholic Neurolysis
Patients received C-arm guided injection of each of the three genicular nerves with 1 ml of a solution containing 70% alcohol in 0.25% lidocaine.
Sponsors & Collaborators
-
Tanta University
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-07-01
- Primary Completion
- 2025-07-01
- Completion
- 2025-07-01
Countries
- Egypt
Study Locations
More Related Trials
-
Comparison of the Efficacy of Chemical Genicular Nerve Neurolysis Using Alcohol or Phenol Versus Radiofrequency Ablation Under Ultrasound Guidance for Pain Management in Patients With Knee Osteoarthritis
NCT06798038 ·Status: NOT_YET_RECRUITING ·Phase: PHASE1
-
Transcutaneous Pulsed Radiofrequency Application Plus Genicular Nerve Block Versus Intraarticular Hyaluronic Acid Injection for Management of Chronic Pain in Knee Osteoarthritis.
NCT06710782 ·Status: COMPLETED ·Phase: NA
-
Radiofrequency Ablation in the Pain Management of Knee Osteoarthritis
NCT05303766 ·Status: UNKNOWN ·Phase: NA
-
Ultrasound-guided Monopolar Versus Bipolar Radiofrequency Ablation for Genicular Nerves in Chronic Knee Osteoarthritis
NCT04112264 ·Status: UNKNOWN ·Phase: NA
-
Comparative Effectiveness of Genicular Nerve Radiofrequency Thermocoagulation and Intra-Articular Pulsed Radiofrequency in the Management of Knee Osteoarthritis Pain
NCT07098455 ·Status: COMPLETED ·Phase: NA
-
Monopolar Versus Biopolar Radiofrequency in OA Knee Pain
NCT05591768 ·Status: COMPLETED ·Phase: NA
-
Percutaneous vs Conventional Radiofrequency Applications for the Treatment of Knee Osteoarthritic Pain
NCT06520371 ·Status: COMPLETED ·Phase: NA
-
Ultra Sound Guided Genicular Nerves Cooled Radiofrequency Ablation in Total Knee Replacement Surgeries
NCT06651762 ·Status: RECRUITING ·Phase: NA
-
Effect of Talar Mobilization With Movement Versus Acupuncture on Knee Pain and Function in the Postmenopausal Women
NCT06051903 ·Status: COMPLETED ·Phase: NA
-
Comparison of Heated vs. Pulsed Radiofrequency Treatment of the Genicular Nerves for Osteoarthritis Knee Pain
NCT04379895 ·Status: UNKNOWN ·Phase: NA
-
Genicular RFT vs Phenol Management in Patients With Knee Osteoarthritis
NCT05908942 ·Status: UNKNOWN
-
Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
NCT06864390 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Genicular Nerve and Intra-articular Radiofrequency Versus Platelet Rich Plasma Injection for Knee Osteoarthritis
NCT03379883 ·Status: UNKNOWN ·Phase: NA
-
Radiofrequency Ablation on Pain Relief of Knee Osteoarthritis
NCT05050396 ·Status: UNKNOWN ·Phase: NA
-
Comparison of Denervation Techniques for the Treatment of Knee Osteoarthritis: Continuous Ablative Radiofrequency Vs. Chemical Denervation with Absolute Alcohol
NCT06858228 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Saphenous Nerve Block Versus Platelet Rich Plasma for Chronic Knee Osteoarthritis
NCT03326544 ·Status: COMPLETED ·Phase: NA
-
Management of Knee Pain by Cooled Radiofrequency in Classical Anatomical Targets and Revised Targets
NCT05363241 ·Status: COMPLETED ·Phase: NA
-
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
NCT06514703 ·Status: RECRUITING ·Phase: NA
-
Efficacy Ultrasound-guided Genicular Nerve Radiofrequency Treatment
NCT06479642 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Genicular Radiofrequency Ablation Versus Pulsed Radiofrequency
NCT06894147 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Adding Deep Front Line Myofascial Release to Selected Exercises in Patients With Knee Osteoarthritis
NCT05812898 ·Status: COMPLETED ·Phase: NA
-
3-point vs 6-point GNRFA for Chronic KOA
NCT05930756 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Efficacy of High Power Laser Versus Low Level Laser in Ultrasonographic and Functional Outcomes in Patients With Knee Osteoarthritis
NCT06419569 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effect of Hip Adductors Isometric Contraction on Knee Extensors Isokinetic Torque in Patellofemoral Pain Syndrome
NCT05083897 ·Status: UNKNOWN
-
The Effect of Radiofrequency Ablation of Genicular Nerves on Postural Stability in Patients With Knee Osteoarthritis
NCT03816124 ·Status: UNKNOWN ·Phase: NA