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BCI With Virtual Reality for Stroke Rehabilitation: A Crossover Study

NCT07374276 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12

Last updated 2026-02-03

No results posted yet for this study

Summary

The goal of this clinical trial is to investigate if training sessions of motor imagery associated with brain-computer interface and motor observation through virtual reality (MI-VR-BCI) can help to improve arm and hand recovery after a stroke. The main questions to answer are:

* Can adding MI-BCI-VR sessions improve upper limb movement?
* Can it help stroke survivors perform daily activities more easily?
* Does this type of training improve brain activity and connections related to movement?

Researchers will compare this type of intervention with motor imagery associated with a standard brain-computer interface intervention (MI-BCI) to see if there are added effects to upper limb function, activity and brain connections.

Participants will :

* Perform two intervention periods in a random order: one with MI-VR-BCI training sessions and other with MI-BCI training sessions. Each period will involve 3 weekly sessions of training, during 6 weeks, with the intervention periods being separated by 3 weeks.
* Complete four assessment sessions: one at the beginning and another at the end of each intervention period.

Conditions

Interventions

DEVICE

Motor Imagery-based Brain-Computer Interface coupled with Virtual Reality (MI-BCI-VR)

The training paradigm will involve motor imagery coupled with EEG-based BCI control and immersive virtual reality (VR) feedback. VR feedback will consist of NeuRow, a first-person perspective training paradigm that allows multimodal visual, auditory and haptic feedback through the use of immersive virtual reality headset and haptic controllers. Sessions will have a frequency of 3 times per week, during 6 weeks.

DEVICE

Motor Imagery-based Brain-Computer Interface (MI-BCI)

The training paradigm will involve motor imagery combined with EEG-based BCI control using a cue-based visual paradigm. Sessions will be conducted three times per week over a period of six weeks.

Sponsors & Collaborators

  • Centro de Medicina de Reabilitação de Alcoitão

    collaborator UNKNOWN

  • Technical University of Lisbon

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-05
Primary Completion
2027-03-31
Completion
2027-03-31

Countries

  • Portugal

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07374276 on ClinicalTrials.gov