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Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae

NCT07369518 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2026-01-27

No results posted yet for this study

Summary

Specimen Collection : Clinical specimens included blood, urine, bronchoalveolar lavage fluid, wound, peritoneal fluid, and tracheal aspirate obtained from patients with suspected bacterial infections collected in dry sterile well-closed plastic cups.

Bacterial identification by Gram stain, culture and biochemical rections

* analysisThe resistance pattern of the isolates will be detected by disc diffusion method.
* phenotypic detection of carbapenemases. • Detection of carbapenem resistance genes (KPC, VIM, IMP, OXA-48, NDM) by conventional PCR.

Conditions

  • ISOLATION OF KLEB. by Culture on macConkey Agar
  • Antibiotic Sensitivity Testing of Different Antibiotics According to Clsi 25
  • Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae
  • Detection of Resistance Gene in Isolates Using Conventional Pcr
  • Detection of Some Virulence Genes Using Conventional Pcr

Interventions

GENETIC

. - Genotypic detection of carbapenemase genes by conventional PCR.

Specimen Collection : Clinical specimens included blood, urine, bronchoalveolar lavage fluid, wound, peritoneal fluid, and tracheal aspirate obtained from patients with suspected bacterial infections collected in dry sterile well-closed plastic cups. Bacterial identification by Gram stain, culture and biochemical rections - analysisThe resistance pattern of the isolates will be detected by disc diffusion method. - phenotypic detection of carbapenemases. • Detection of carbapenem resistance genes (KPC, VIM, IMP, OXA-48, NDM) by conventional PCR.

Sponsors & Collaborators

  • Sohag University

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-31
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07369518 on ClinicalTrials.gov