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Clinical Management Strategies for Patients With Cirrhosis and Esophagogastric Varices Complicated by Early-stage Upper Gastrointestinal Cancer

NCT07368309 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 206

Last updated 2026-01-26

No results posted yet for this study

Summary

Managing early-stage upper gastrointestinal cancer in patients with liver cirrhosis and esophagogastric varices (EGV) poses substantial clinical challenges. Although endoscopic submucosal dissection (ESD) is an established treatment for these early cancers, its efficacy and safety in this high-risk population are poorly defined. Therefore, this study aims to investigate optimal screening and treatment strategies for early-stage upper gastrointestinal cancer in cirrhotic patients with EGV. Perioperative outcomes were compared between the two groups.

Conditions

  • Cirrhosis
  • Esophagogastric Varices
  • Early-stage Upper Gastrointestinal Cancer

Sponsors & Collaborators

  • Southwest Hospital, China

    collaborator OTHER

  • Shanxi Coal Central Hospital

    collaborator UNKNOWN

  • Beijing Friendship Hospital

    collaborator OTHER

  • The Second Affiliated Hospital of Chongqing Medical University

    collaborator OTHER

  • Tongji Hospital Affiliated to Tongji Medical College of HUST

    collaborator UNKNOWN

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    collaborator OTHER

  • Renmin Hospital of Wuhan University

    lead OTHER

Principal Investigators

  • Mingkai Chen · Renmin Hospital of Wuhan University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-01
Primary Completion
2024-08-01
Completion
2025-12-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07368309 on ClinicalTrials.gov