Liver Resection for Patients With Hepatocellular Carcinoma and Clinically Significant Portal Hypertension
NCT06245798 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3000
Last updated 2024-02-07
Summary
Clinically significant portal hypertension limits the therapeutic options for hepatocellular carcinoma (HCC), which is closely associated with patient prognosis. HCC patients with CPSH are heterogeneous and treatment allocation remains controversial. The aim of this study was to compare the survival benefits of liver resection (LR) and transarterial chemoembolisation (TACE) in these populations.
Conditions
- Hepatic Carcinoma
Interventions
- PROCEDURE
-
transarterial chemoembolisation
During transarterial chemoembolisation(TACE), a vascular catheter was selectively inserted into the tumour-feeding artery with an injection containing a mixture of doxorubicin (10-50 mg) and lipiodol (2-20 mL), followed by embolisation using gelatin sponge particles. TACE was repeated when residual viable tumours were confirmed or new lesions developed in patients with adequate liver function
Sponsors & Collaborators
-
Tang-Du Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-01-01
- Primary Completion
- 2023-04-01
- Completion
- 2023-12-01
Countries
- China
Study Locations
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