Study to Compare and Evaluate the Safety and Pharmacokinetics After Subcutaneous Injection of HUC2-676 or HUC2-676-R in Healthy Adult Subjects
NCT07337174 · Status: NOT_YET_RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 40
Last updated 2026-01-13
Summary
The trial uses a randomized, open-label, single-dose administration per period, and a 2 x 2 crossover design where subjects receive both treatments sequentially with a washout.
Conditions
Interventions
- DRUG
-
HUC2-676
subcutaneous injection
- DRUG
-
HUC2-676-R
subcutaneous injection
Sponsors & Collaborators
-
Huons Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Park · Chungbuk National University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 19 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-01-25
- Primary Completion
- 2026-03-24
- Completion
- 2026-03-24
More Related Trials
-
A Study of HS-20094 in Chinese Adults with Overweight or Obesity
NCT06839664 ·Status: RECRUITING ·Phase: PHASE3
-
A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the Skin
NCT06064006 ·Status: COMPLETED ·Phase: PHASE2
-
A Two-Part First-In-Human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GUB014295
NCT06144684 ·Status: COMPLETED ·Phase: PHASE1
-
Ph 2a Study of HU6 on Energy Metabolism, Muscle and Liver Substrate Metabolism, and Mitochondrial Function in Subjects Who Are Overweight or Obese With Type 2 Diabetes
NCT06104358 ·Status: WITHDRAWN ·Phase: PHASE2
-
Phase Ib Clinical Study of HDM1005 Injection
NCT06637020 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity
NCT07243171 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Metabolism and Excretion of Liraglutide in Healthy Male Volunteers
NCT01517568 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity
NCT06478563 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
NCT06577766 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants When Injected Under the Skin.
NCT07121153 ·Status: COMPLETED ·Phase: PHASE1
-
A First-in-human Research Study on How NNC0662-0419 Works in People Living With Overweight or Obesity
NCT06737536 ·Status: COMPLETED ·Phase: PHASE1
-
A Two Part Trial Investigating an Anti-obesity Drug in Overweight/Obese Male and Female Healthy Volunteers
NCT01044108 ·Status: TERMINATED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity
NCT07142707 ·Status: RECRUITING ·Phase: PHASE1
-
A Trial of HRS-5817 in Obese Participants
NCT07238647 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
A Study of IBI362 9 mg in Chinese Adults With Obesity
NCT06164873 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study of ZT002 Injection With Subjects With Overweight or Obesity
NCT07020884 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of ZT002 Injection in Participants With Overweight or Obesity
NCT06371326 ·Status: COMPLETED ·Phase: PHASE1
-
This Study Will Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of MET097 in Adult Participants With Overweight or Obesity
NCT06857617 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control Group
NCT01511185 ·Status: COMPLETED ·Phase: PHASE1
-
UBT251 Injection Phase II Study (Overweight or Obesity)
NCT07177469 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
NCT07284875 ·Status: RECRUITING ·Phase: PHASE3
-
Phase II Study of THDBH120 Injection in Overweight or Obese Subjects
NCT07036601 ·Status: RECRUITING ·Phase: PHASE2
-
The Safety, Tolerability, and Pharmacokinetics of of SYH9017 in Chinese Participants With Overweight and Obesity
NCT06830343 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Test Whether Different Doses of BI 456906 Help People With Overweight or Obesity to Lose Weight
NCT04667377 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation
NCT06756490 ·Status: RECRUITING ·Phase: PHASE1