Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
NCT07284875 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1800
Last updated 2026-05-08
Summary
The primary objective of the study is to determine the effects of KAI-9531 subcutaneous (SC) injection once weekly compared to placebo on percent change in body weight.
Conditions
Interventions
- DRUG
-
KAI-9531
SC Injection
- DRUG
-
SC Injection
Sponsors & Collaborators
-
Kailera
lead INDUSTRY
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-12-18
- Primary Completion
- 2028-02-28
- Completion
- 2028-03-27
- FDA Drug
- Yes
Countries
- United States
- Australia
- New Zealand
Study Locations
More Related Trials
-
A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the Skin
NCT06064006 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of TG103 Injection in Non-diabetic Overweight or Obesity
NCT05997576 ·Status: COMPLETED ·Phase: PHASE3
-
Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin
NCT02963922 ·Status: COMPLETED ·Phase: PHASE3
-
The Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight Patients
NCT04605861 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of ZT002 Injection With Subjects With Overweight or Obesity
NCT07020884 ·Status: COMPLETED ·Phase: PHASE2
-
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity
NCT06577766 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.
NCT00396448 ·Status: TERMINATED ·Phase: PHASE3
-
A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
NCT07081958 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase III Clinical Study Comparing the Efficacy and Safety of GZR18 Injection and Semaglutide (Wegovy®) in Adult Obese or Overweight Subjects
NCT07150975 ·Status: RECRUITING ·Phase: PHASE3
-
A Long-Term Study To Examine The Effects Of CP-945,598 On Weight Loss And Safety
NCT00375401 ·Status: TERMINATED ·Phase: PHASE3
-
Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.
NCT03856047 ·Status: COMPLETED ·Phase: PHASE2
-
A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or Obesity
NCT06478563 ·Status: COMPLETED ·Phase: PHASE1
-
A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants When Injected Under the Skin.
NCT07121153 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes
NCT05950516 ·Status: UNKNOWN ·Phase: PHASE3
-
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
NCT02453711 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Liraglutide on Body Weight in Obese Subjects or Overweight Subjects With Co-morbidities
NCT04487743 ·Status: UNKNOWN ·Phase: PHASE3
-
A Study of HS-20094 in Chinese Adults with Overweight or Obesity
NCT06839664 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of TG103 Injection in the Management of Non-diabetic Overweight or Obesity
NCT06226090 ·Status: COMPLETED ·Phase: PHASE2
-
A Research Study Investigating NNC0247-0829 for Weight Management in People With Overweight or Obesity
NCT04010786 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of HRS9531 Injections in Overweight or Obese Subjects
NCT06054698 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
NCT06124807 ·Status: COMPLETED ·Phase: PHASE2
-
An Investigational Drug Study in Obese (Considerably Overweight) Patients (0364-006)
NCT00109148 ·Status: COMPLETED ·Phase: PHASE2
-
A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients
NCT00391196 ·Status: TERMINATED ·Phase: PHASE3
-
Research Study of a New Medicine (NNC9204-1706) in People With Overweight or Obesity
NCT03661879 ·Status: COMPLETED ·Phase: PHASE1
-
Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male Subjects
NCT02235961 ·Status: COMPLETED ·Phase: PHASE1