MedTrace Logo

Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy

NCT07328607 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2026-01-21

No results posted yet for this study

Summary

This is a monocentric, prospective, randomized controlled trial comparing the safety and efficacy of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD). The study aims to determine the morbimortality of the laparoscopic approach compared to the gold standard open approach in adult patients with pancreatic or periampullary lesions.

Conditions

Interventions

PROCEDURE

Open Pancreaticoduodenectomy

Open Pancreaticoduodenectomy with lymphadenectomy and reconstruction via open technique.

PROCEDURE

Laparoscopic Pancreaticoduodenectomy

Minimally invasive Whipple procedure using 6 trocars, with specimen extraction via Pfannenstiel incision.

Sponsors & Collaborators

  • Minia University

    lead OTHER

Principal Investigators

  • Saleh K Saleh, MD · Minia University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-01-17
Primary Completion
2028-01-15
Completion
2028-04-15

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07328607 on ClinicalTrials.gov