Evaluation of Irisin Levels in Adult Forearm Fracture Surgery Under Infraclavicular Block and General Anesthesia
NCT07324681 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2026-01-09
Summary
This randomized prospective study evaluates the effect of general anesthesia versus infraclavicular nerve block on perioperative serum irisin levels in adults undergoing forearm fracture surgery. Irisin levels will be measured preoperatively, at 30 minutes postoperatively, and at 24 hours postoperatively. The association between irisin changes and fracture healing will be explored as a secondary outcome.
Conditions
- Inflamation
- Healing
- Angiogenesis
Interventions
- PROCEDURE
-
General Anesthesia (GA)
General anesthesia administered according to institutional routine; anesthetic drugs and doses will be recorded.
- PROCEDURE
-
Infraclavicular Brachial Plexus Blocks
Ultrasound-guided infraclavicular block performed preoperatively; details of technique, local anesthetic drugs and doses will be recorded.
Sponsors & Collaborators
-
Ankara City Hospital Bilkent
lead OTHER
Principal Investigators
-
sumru sekerci, professor · Ankara Bilkent City Hospital Department of Anesthesiology and Reanimation, Ankara, Çankaya
Study Design
- Allocation
- RANDOMIZED
- Purpose
- OTHER
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-01-25
- Primary Completion
- 2026-05-02
- Completion
- 2026-05-05
More Related Trials
-
Evaluation of Cerebral Oxygenation During Orthopedic Surgeries Performed in the Beach Chair Position Under General Anesthesia
NCT07270341 ·Status: RECRUITING
-
Anesthesia for Emergency Orthopedic Surgery
NCT02820922 ·Status: UNKNOWN
-
Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia
NCT07040540 ·Status: COMPLETED
-
The Role of Perfusion Index in Defining Postoperative Shivering
NCT06843031 ·Status: ACTIVE_NOT_RECRUITING
-
Relationship Between ORI and Blood Transfusion in Spinal Surgery
NCT05868447 ·Status: UNKNOWN
-
Low-Flow Desflurane Anesthesia and Its Effects on BIS and Postoperative Cognitive Functions
NCT07212543 ·Status: ACTIVE_NOT_RECRUITING
-
Effect of Anesthesia Technique on Surgical View in Shoulder Arthroscopy
NCT07343414 ·Status: NOT_YET_RECRUITING
-
Measurement of Cut-off Perfusion Index Value in Infraclavicular Blocks
NCT05234541 ·Status: UNKNOWN
-
Influence of Variations of Systemic Venous Return on Analgesia Nociception Index (ANI) During General Anaesthesia
NCT02193412 ·Status: COMPLETED ·Phase: NA
-
Analgesia Nociception Index (ANI) in Intracranial Surgical Anesthesia
NCT06752824 ·Status: COMPLETED
-
Effects of Preoperative Fasting on ECG and Vital Parameters
NCT02773199 ·Status: COMPLETED
-
Spinal Versus General Anesthesia and Inflammatory Response Measured by Delta Neutrophil Index in Total Knee Arthroplasty: An Observational Study
NCT07214558 ·Status: COMPLETED
-
Low Flow Anesthesia Without Initial High Flow Phase
NCT03955406 ·Status: COMPLETED ·Phase: NA
-
Effect of Tourniquet Use on ICEB and ICEBc in Upper Extremity Surgeries
NCT06936150 ·Status: COMPLETED
-
Effect of Anesthesia Method on Neutrophil-Lymphocyte Ratio
NCT05628935 ·Status: COMPLETED
-
Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery
NCT06520943 ·Status: NOT_YET_RECRUITING
-
Evaluation of the Effects of Preoperative Anxiety in Patients Undergoing Total Intravenous Anesthesia (TIVA)
NCT04690764 ·Status: UNKNOWN
-
General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery
NCT06482996 ·Status: RECRUITING
-
Evaluation of The Relationship Between Perioperative Hypothermia and Emergence Agitation
NCT06543134 ·Status: RECRUITING
-
Comparison of Calcium Channel Blockers and Beta Blockers on Tourniquet-induced Hypertension During Intravenous Regional Anesthesia
NCT02319161 ·Status: COMPLETED
-
Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
NCT05476198 ·Status: COMPLETED ·Phase: NA
-
Impact of Smoking on Ultrasound-Guided Infraclavicular Brachial Plexus Block Onset and Duration
NCT06755229 ·Status: NOT_YET_RECRUITING
-
Inflammatory Response Under Spinal vs General Anesthesia in PCNL: NLR, RDW, LAR.
NCT07205224 ·Status: COMPLETED
-
Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery
NCT06070480 ·Status: COMPLETED ·Phase: NA
-
Non-invasive Assessment of Immediate Postoperative Analgesia Using Analgesia/Nociception Index (ANI)
NCT01633320 ·Status: COMPLETED