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Analgesia Nociception Index (ANI) in Intracranial Surgical Anesthesia

NCT06752824 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75

Last updated 2024-12-31

No results posted yet for this study

Summary

In our study, 75 patients aged 18-80 years, classified as ASA I-II risk groups, who underwent intracranial surgery performed by the Department of Neurosurgery at Trakya University Faculty of Medicine Hospital, were included. After the patients were positioned on the neurosurgical operating table, heart rate, systolic blood pressure, diastolic blood pressure, peripheral oxygen saturation, and entropy values were measured in all cases. Baseline values were recorded for patients who underwent ANI (Analgesia Nociception Index) monitoring. In both groups, entropy values were targeted to remain within the range of 40-60. In the ANI group, ANI values were maintained between 50-70.

Patients were divided into two groups based on the intraoperative monitoring method applied: the ANI group (n=38) and the control group (n=37). All patients underwent entropy monitoring, while ANI monitoring was exclusively used in the ANI group for pain management. In the ANI group, remifentanil infusion adjustments were made to keep ANI values within the 50-70 range.

This study aimed to compare perioperative opioid consumption, postoperative pain, and recovery from anesthesia in patients undergoing intracranial surgery who received general anesthesia and analgesia management guided by either entropy monitoring alone or a combination of entropy and ANI monitoring.

Conditions

  • Pain, Postoperative
  • Analgesia
  • Supratentorial Brain Tumor
  • Infratentorial Neoplasms
  • Pituitary Neoplasms
  • Intraoperative Monitoring
  • Pain Monitoring

Interventions

DEVICE

ANALGESIA NOCICEPTION INDEX MONITORING

INTRACRANIAL SURGERY

Sponsors & Collaborators

  • Trakya University

    lead OTHER

Principal Investigators

  • SEVTAP HEKİMOĞLU ŞAHİN · Trakya University

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2024-01-01
Completion
2024-01-01
FDA Device
Yes

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06752824 on ClinicalTrials.gov