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Posterior Chain Responses to Gastrocnemius DOMS

NCT07324395 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2026-01-07

No results posted yet for this study

Summary

The goal of this clinical trial is to learn how delayed onset muscle soreness (DOMS) in the calf muscle (gastrocnemius) affects the muscles of the posterior chain and physical performance in healthy young adults. The main questions the study aims to answer are:

Does DOMS in the calf muscle change the biomechanical properties (tone, stiffness, elasticity) of other muscles in the posterior chain?

Does DOMS lower trunk endurance, muscle strength, balance, or jump performance?

Participants will:

Take part in a gastrocnemius exercise protocol designed to safely create DOMS

Complete repeated assessments at baseline, immediately after exercise, and at 24, 48, and 72 hours

Have their muscle properties measured with a handheld device

Complete trunk endurance tests, muscle strength tests, balance tests, and a vertical jump test

Provide a blood sample to measure creatine kinase (a marker of muscle damage)

This research may help clinicians better understand how soreness in one muscle can influence the whole posterior chain and may guide safer training and recovery strategies.

Conditions

  • Delayed Onset Muscle Soreness (DOMS)
  • Healthy

Interventions

OTHER

Gastrocnemius DOMS Induction Protocol

Participants will complete an eccentric exercise protocol to safely induce delayed onset muscle soreness (DOMS) in the gastrocnemius muscle. The protocol includes: Exercise performed bilaterally, starting with the dominant leg Three sets of eccentric heel-lowering movements A 5-minute rest period between sets Participants place the foot on a step and lower the heel for 3 seconds using eccentric contraction The heel is lowered until no further downward motion is possible The opposite leg is used only to lift the body back to the starting position in 1 second A metronome set to 60 beats per minute is used to control movement speed Each set ends when the participant can no longer maintain the required tempo Participants are instructed to avoid physical activity and not take any pain-relieving medication during the 72-hour follow-up period. Intervention Model Description: All participants receive the same DOMS induction protocol.

Sponsors & Collaborators

  • The Scientific and Technological Research Council of Turkey

    collaborator OTHER

  • Ebru Aloğlu Çiftçi

    lead OTHER

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
25 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-12-20
Primary Completion
2025-03-20
Completion
2025-04-25

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07324395 on ClinicalTrials.gov