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Comparison of Cough Response Between Tegilidine and Sufentanil as Pre-induction Agents in General Anesthesia

NCT07323043 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 190

Last updated 2026-02-04

No results posted yet for this study

Summary

In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled, double-blind study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or tegilidine. The cough was graded based on the frequency and duration: Grade I, no cough; Grade II, a single mild cough; Grade III, multiple coughs with duration \<1 second; Grade IV, continuous coughing with a duration \>15 seconds.

Conditions

  • General Anesthetic Drug Adverse Reaction

Interventions

DRUG

Tegilidine

Inject Tegilidine in the induction of general anesthesia

DRUG

Sufentanil

Inject Sufentanil in the induction of general anesthesia

Sponsors & Collaborators

  • The First People's Hospital of Lianyungang

    lead OTHER

Principal Investigators

  • Xiaobao Zhang, Doctor · Xuzhou Medical University Affiliated Hospital of Lianyungang: Lianyungang No 1 People's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-15
Primary Completion
2026-05-16
Completion
2026-06-16

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07323043 on ClinicalTrials.gov