MedTrace Logo

Effects of Different Vitamin D3 Formulations in Vitamin D-Deficient Adults

NCT07317830 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2026-01-05

No results posted yet for this study

Summary

This randomized controlled superiority pilot trial will evaluate the efficacy of two vitamin D3 formulations administered over eight weeks in adults with subclinical or clinical vitamin D deficiency. The study will compare changes in serum 25-hydroxyvitamin D concentrations between formulations, as well as the proportion of participants who will achieve vitamin D sufficiency. Both formulations are expected to improve vitamin D status, with the hypothesis that one formulation will demonstrate superior bioavailability, resulting in greater and faster increases in circulating 25-hydroxyvitamin D. The findings will provide preliminary evidence to inform formulation selection and dosing strategies for correcting vitamin D deficiency and will support the design of larger, confirmatory trials.

Conditions

  • Vitamin D Deficiency

Interventions

DIETARY_SUPPLEMENT

Experimental 1 (powdered supplement)

Active powdered ingredient (2,000 IU/d)

DIETARY_SUPPLEMENT

Experimental 2 (oily supplement)

Active oily ingredient (2,000 IU/d)

Sponsors & Collaborators

  • Center for Health Sciences, Serbia

    lead OTHER

Principal Investigators

  • Sergej Ostojic, MD, PhD · University of California, Los Angeles

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-15
Primary Completion
2026-05-31
Completion
2026-06-15

Countries

  • Serbia

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07317830 on ClinicalTrials.gov