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Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism(SCOPE)

NCT07298954 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 456

Last updated 2025-12-24

No results posted yet for this study

Summary

This study is a prospective, multicenter, randomized clinical trial aimed to compare the impact of three AVS diagnostic strategies on the clinical outcomes of patients with primary aldosteronism. The strategies include sequential combined AVS (non-ACTH-stimulated followed by ACTH-stimulated AVS), non- ACTH-stimulated AVS alone, and ACTH-stimulated AVS alone. The findings of this study will provide critical evidence for the clinical practice standards of AVS.

Conditions

  • Primary Aldosteronism

Interventions

DIAGNOSTIC_TEST

sequential combined AVS

non-ACTH-stimulated followed by ACTH-stimulated AVS

Sponsors & Collaborators

  • First Affiliated Hospital of Kunming Medical University

    collaborator OTHER

  • The First Affiliated Hospital of Nanchang University

    collaborator OTHER

  • The People's Hospital of Chuxiong Yi Autonomous Prefecture

    collaborator UNKNOWN

  • Shumin Yang

    lead OTHER

Principal Investigators

  • Shumin Yang · the Chongqing Primary Aldosteronism Study (CONPASS) Group

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-12-25
Primary Completion
2027-12-31
Completion
2028-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07298954 on ClinicalTrials.gov