Analysis of Methylomic Features and Prognostic Risk Prediction in Patients With Hepatitis B-related Acute-on-chronic Liver Failure
NCT07275554 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2025-12-10
Summary
This study aims to investigate the methylomic features of patients with hepatitis B-related acute-on-chronic liver failure and establish and validate a prognostic risk prediction classification model. The findings are of significant importance for guiding clinical practice and improving patient prognosis. Additionally, a methylomics-based classifier model for liver failure will be developed for disease prognosis analysis and clinical assessment, with the potential to enhance the diagnostic efficiency of liver failure.
Conditions
- HBV Related Acute-on-chronic Liver Failure
- HBV-related Liver Cirrhosis
- HBV (Hepatitis B Virus)
Sponsors & Collaborators
-
Qilu Hospital of Shandong University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-12-31
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- China
Study Locations
More Related Trials
-
MR Elastography for Assessing Liver Fibrosis in Chronic Hepatitis B
NCT06779058 ·Status: RECRUITING
-
Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD
NCT05766449 ·Status: RECRUITING
-
Cost Effective Non Invasive Diagnostic Modalities and Predictive Model for Development and Progression of Fibrosis Among Patients With Hepatitis B, Hepatitis C Infection or Non Alcoholic Fatty Liver Disease
NCT02658786 ·Status: WITHDRAWN
-
Multiomics Study of Fibrosis Factors After Liver Transplantation and Exploration of Fibrosis Methylation Biomarkers
NCT05926778 ·Status: UNKNOWN
-
Steatohepatitis in Chronic Hepatitis B
NCT05317260 ·Status: COMPLETED
-
Risk of Hepatocellular Carcinoma in Patient With Liver Cirrhosis
NCT03083002 ·Status: UNKNOWN
-
Characteristics and Risk Factors for Invasive Fungal Infection With Acute-on-chronic Hepatitis B Liver Failure
NCT06190002 ·Status: NOT_YET_RECRUITING
-
Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver Disease
NCT03635541 ·Status: UNKNOWN
-
Prospective Stuy in Evaluating Hepatic Fibrosis Related to Hepatitis B Virus Using Non-invasive Parameters
NCT01962155 ·Status: COMPLETED
-
A Single-center, Prospective Cohort Study on the Differentiation of Benign and Malignant Bile Duct Stenosis Based on Bile and Peripheral Blood cfDNA Methylation Profiles
NCT06115655 ·Status: RECRUITING
-
Application of the Stem Cell Therapy in the End Stage Liver Disease and Assessment Its Consequences in the Quality of Live Style as Well as Development of HCC.
NCT01729221 ·Status: UNKNOWN
-
Prophylactic Treatment of Hepatic Dysplastic Nodules in HBsAg Positive Patients
NCT02793791 ·Status: UNKNOWN ·Phase: NA
-
Better Diagnostic Tools for Children and Adolescents With Acute Liver Failure and Chronic Liver Insufficiency
NCT03509194 ·Status: UNKNOWN
-
Prognosis Value of Non-invasive Methods for the Diagnosis of Chronic Liver Disease
NCT02060565 ·Status: RECRUITING
-
An Observational Study To Assess Liver Fibrosis Stages in Patients With Chronic Hepatitis C Infection
NCT01671046 ·Status: COMPLETED
-
Prediction Model Based on Computed Tomography Liver Volume for the Short-term Mortality in Hepatitis B Related Acute-on-Chronic
NCT03977857 ·Status: COMPLETED
-
Assessment of Liver Fibrosis and Prognosis in Chinese Patients With CHB Infection Using STE/STQ Elastography
NCT03530657 ·Status: UNKNOWN
-
To Explore the Value of New MR Technology in Non-invasive Quantitative Assessment of Systemic Metabolism, Disease Status and Prognosis in Patients With Metabolic-Associated Fatty Liver Disease
NCT07149571 ·Status: RECRUITING
-
Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease
NCT02863757 ·Status: RECRUITING
-
Clinical Features and Natural History of Acute-on-Chronic Liver Failure in Korean Patients With Chronic Liver Disease
NCT02650011 ·Status: SUSPENDED
-
Usefulness of Multi-parametric, Quantitative MR Imaging for Staging of Hepatic Fibrosis in the Patients With Chronic Hepatitis
NCT01981421 ·Status: UNKNOWN
-
Stratification of Patients With Chronic Liver Disease Using Multi Spectral CT
NCT01825213 ·Status: COMPLETED
-
A Multicenter Prospective Study of Application of Platelet Mapping in Acute-on-chronic-liver Failure in China
NCT04119973 ·Status: COMPLETED
-
A Prospective Study of ¹⁸F-DFA PET Imaging for the Assessment of Liver Injury
NCT07050550 ·Status: RECRUITING
-
Study on Prognosis of Acute-on-chronic Liver Failure Complicated by Bacterial or Fungal Infection
NCT06437067 ·Status: RECRUITING