Surgical Versus Percutaneous Revascularization in Patients With Reduced Left Ventricular Function (STICH 3.0-NL)
NCT07269366 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 358
Last updated 2026-05-12
Summary
This randomized multicenter trial compares coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) in 358 patients with ischemic left ventricular dysfunction and multivessel coronary disease. The study evaluates differences in survival, major cardiovascular events, and quality of life over 4 years, and contributes to the international STICH 3.0 collaboration assessing long-term outcomes.
Conditions
- Coronary Artery Disease
- Coronary Artery Disease (CAD)
- Multivessel Coronary Artery Disease
- CABG
- CABG in Low EF
- Heart Failure
- PCI
- Revascularization
Interventions
- PROCEDURE
-
CABG
CABG (coronary artery bypass grafting)
- PROCEDURE
-
PCI
PCI (percutaneous coronary intervention)
Sponsors & Collaborators
-
Dutch Heart Foundation
collaborator OTHER -
University Medical Center Groningen
lead OTHER
Principal Investigators
-
Erik Lipsic, Dr · University Medical Center Groningen
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2026-05-31
- Primary Completion
- 2034-05-31
- Completion
- 2034-05-31
Countries
- Netherlands
Study Locations
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