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Disease Characteristics of R-CAD

NCT07239921 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 52

Last updated 2025-11-28

No results posted yet for this study

Summary

The present case-control study is designed to investigate the disease characteristics of rapidly progressive coronary artery disease (R-CAD) by comparing the demographics, clinical features, lab results, imaging findings, and prior treatment between patients in the case group (approximately 34 patients with R-CAD) and those in the control group (approximately 18 patients with non-rapidly progressive coronary artery disease \[NR-CAD\]).

Conditions

  • Coronary Artery Disease
  • Coronary Artery Disease Progression
  • Coronary Stenosis
  • Coronary Restenosis
  • Coronary Stent Occlusion
  • Myocardial Revascularization
  • Percutaneous Coronary Intervention

Interventions

DIAGNOSTIC_TEST

Protocol-defined Examinations and Evaluations

Lab tests (blood and urine and stool routine tests, hepatic and renal and thyroid function tests, tests for metabolic markers, tests for cardiac biomarkers, thrombosis-related tests, rheumatology tests, tests for inflammation markers), electrocardiography, echocardiography, 6-minute walk test, vascular ultrasound, coronary angiography, optical coherence tomography (OCT), fibroblast activation protein inhibitor positron emission tomography/computed tomography (FAPI-PET/CT), photon-counting detector coronary computed tomography angiography (PCD-CCTA), tests for exploratory biomarkers.

Sponsors & Collaborators

  • Peking Union Medical College Hospital

    lead OTHER

Principal Investigators

  • Zhenyu Liu, M.D. · Peking Union Medical College Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-11-30
Primary Completion
2026-10-31
Completion
2026-10-31

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Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07239921 on ClinicalTrials.gov