The Role of TRP Channels in DPN
NCT07237022 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20
Last updated 2025-11-19
Summary
The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers. The vascular response will be characterized in terms of response over time, dose-response, inter-foot and inter-period reproducibility.
Conditions
- Physiological Responses
Interventions
- OTHER
-
Cinnamaldehyde
A 10% and 30% cinnamaldehyde solution is topically applied on foot skin.
- OTHER
-
Allyl isothiocyanate (AITC)
A 15% and up to 30% AITC solution is topically applied on foot skin.
- OTHER
-
Capsaicin
A 1.5% and 5% capsaicin solution is topically applied on foot skin.
Sponsors & Collaborators
-
Universitaire Ziekenhuizen KU Leuven
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-10-08
- Primary Completion
- 2026-05-31
- Completion
- 2026-08-31
Countries
- Belgium
Study Locations
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