The Role of TRP Channels in DPN

NCT07237022 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2025-11-19

No results posted yet for this study

Summary

The study aims to characterize the vascular response upon topical application of cinnamaldehyde, allyl isothiocyanate and capsaicin on feet skin in healthy volunteers. The vascular response will be characterized in terms of response over time, dose-response, inter-foot and inter-period reproducibility.

Conditions

  • Physiological Responses

Interventions

OTHER

Cinnamaldehyde

A 10% and 30% cinnamaldehyde solution is topically applied on foot skin.

OTHER

Allyl isothiocyanate (AITC)

A 15% and up to 30% AITC solution is topically applied on foot skin.

OTHER

Capsaicin

A 1.5% and 5% capsaicin solution is topically applied on foot skin.

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-08
Primary Completion
2026-05-31
Completion
2026-08-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07237022 on ClinicalTrials.gov