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The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream

NCT01883102 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 1

Last updated 2013-06-21

No results posted yet for this study

Summary

This is a study of epidermal (the outer most layer) nerve fibers (ENFs) in the skin of the body; counts of which are used to determine a disease of nerves called "small nerve fiber neuropathy."

Capsaicin is approved by the Food and Drug Administration (FDA) for pain relief. Since 0.1% capsaicin is known to cause ablation (removal) of ENFs, this study will test whether such ablation results in relief of spontaneous pain, touch, or heat-pain.

Conditions

Interventions

DRUG

Capsaicin 0.1%

Cream will be cleansed from sites A and B with soap and water each morning before reapplying.

DRUG

Placebo

Cream will be cleansed from sites A and B with soap and water each morning before reapplying.

Sponsors & Collaborators

Principal Investigators

  • Peter Dyck, MD · Mayo Clinic

Study Design

Allocation
NON_RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
FACTORIAL

Eligibility

Min Age
39 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-06-30
Primary Completion
2013-06-30
Completion
2013-06-30

Countries

  • United States

Study Locations

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Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01883102 on ClinicalTrials.gov