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Exploring the Cutaneous Immune Response to Skin Massage in Early Life

NCT07228728 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 109

Last updated 2026-02-11

No results posted yet for this study

Summary

This project aims to study whether regular skin massage in babies induces cutaneous inflammation and whether this inflammatory response is amplified in those receiving daily (vs bi-weekly or no) skin massage over an 8 week period. Specifically, it aims to:

1. Establish if massage increases /decreases immune signals in the skin.
2. Clarify if the effects of massage are enhanced with the frequency of massage. 3.) Assess changes in skin biology as a consequence of skin massage. 4.) Determine if massage impacts skin barrier function in the early years of life.

Conditions

  • Skin Massage

Interventions

OTHER

Skin Massage with Product

Application of product containing oil- and aqueous-based components to baby's skin followed by a standardized massage.

Sponsors & Collaborators

  • Guy's and St Thomas' NHS Foundation Trust

    collaborator OTHER

  • Rosetrees Trust

    collaborator OTHER

  • Stoneygate Trust

    collaborator UNKNOWN

  • King's College London

    lead OTHER

Principal Investigators

  • Carsten Flohr · Guy's and St Thomas' NHS Foundation Trust

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
0 Months
Max Age
6 Months
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-01-02
Primary Completion
2027-03-30
Completion
2027-04-30

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07228728 on ClinicalTrials.gov