Effectiveness Study of Integrative Treatment for Pediatric Pneumonia

Summary

The purpose of this study is to evaluate the effectiveness of traditional Chinese medicine for treatment of pediatric pneumonia. It is a multicenter randomized controlled trial.

Conditions

• Pneumonia

Interventions

OTHER

Fuxiong San

external application; 8-10cm wide, 0.3-0.5cm thick; 10mins for patient aged 1 to 3-year old; 15mins for those aged 3 to 5-year old; once daily

DRUG

Xiyanping injection

ivd. 5 to 10 mg/(kg•d), plus 5% Glucose Injection, 80 to 100 ml, ivd. Once a day injection.

DRUG

Ribavirin Injection

ivd. 10 to 20 mg/(kg•d), plus 5% Glucose Injection, 80 to 100 ml, ivd. Once a day injection.

DRUG

Xiaoer Qingfei Heji (mixture)

children aged 6 months to 1 year old: 10 ml, orally taken three times daily; children aged 1 to 3 year old: 15 ml, orally taken three times daily; children aged 3 to 5 year old: 20 ml, orally taken three times daily;

DRUG

Zhi Ke San

children aged 6 months to 1 year old: 0.5g, orally taken three times daily; children aged 1 to 3 year old: 1.5g, orally taken three times daily; children aged 3 to 5 year old: 2.0g, orally taken three times daily;

DRUG

Hua Tan San

children aged 6 months to 1 year old: 0.5g, orally taken three times daily; children aged 1 to 3 year old: 1.5g, orally taken three times daily; children aged 3 to 5 year old: 2.0g, orally taken three times daily;

DRUG

Guaifenesin Syrup

children aged 6 months to 1 year old: 3ml, orally taken three times daily; children aged 1 to 3 year old: 5ml, orally taken three times daily; children aged 3 to 5 year old: 8ml, orally taken three times daily;

DRUG

Ibuprofen Suspension

taken under prescription

DRUG

salbutamol

taken under prescription

Sponsors & Collaborators

• Beijing University of Chinese Medicine

  collaborator OTHER

• Liaoning University of Traditional Chinese Medicine

  lead OTHER

Principal Investigators

• Xuefeng Wang, Ph.D. · Affiliated Hospital of Liaoning University of TCM

• Zhenqi Wu · Affiliated Hospital of Liaoning University of TCM

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

6 Months

Max Age

59 Months

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2011-12-31

Primary Completion

2013-07-31

Completion

2013-08-31

Countries

• China

Study Locations