Accelerometer Measured Early Recovery After Prolapse Surgery

Summary

The AccelERate study will evaluate the physical recovery of patients who have undergone Pelvic Organ Prolapse (POP) surgery. This will be evaluated via a self-reported recovery questionnaire completed daily. Participants will wear an accelerometer device on their non-dominant wrist and be given either routine or exercise-focused postoperative instructions. The primary outcome will be a comparison of the number of days needed to reach self-reported "mostly recovered" status between randomly assigned instruction groups.

Conditions

• Pelvic Organ Prolapse
• Pelvic Organ Prolapse (POP)
• Pelvic Organ Prolapse Vaginal Surgery
• Pelvic Organ Prolapse, Patient Education

Interventions

BEHAVIORAL

Postoperative Exercise regimen

The intervention arm will be instructed to perform 30 minutes of medium intensity exercise (vigorous enough to cause shortness of breath, but light enough to be able to maintain a conversation) starting on postoperative day 3 and continuing at least 5 times weekly for 6 weeks. Participants in the intervention group will be allowed to select their preferred physical activity, and the activity will be performed without supervision. Participants in the control group will be given typical postoperative instructions with gradual resumption of activity.

Sponsors & Collaborators

• RTI International

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• University of Chicago

  collaborator OTHER

• Duke University

  collaborator OTHER

• Women and Infants Hospital of Rhode Island

  collaborator OTHER

• University of Pennsylvania

  collaborator OTHER

• Kaiser Permanente

  collaborator OTHER

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• NICHD Pelvic Floor Disorders Network

  lead NETWORK

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

99 Years

Sex

FEMALE

Healthy Volunteers

No

Timeline & Regulatory

Start

2025-10-02

Primary Completion

2027-06-30

Completion

2028-03-31

Countries

• United States

Study Locations