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The Effect of Short-term Supplementation of OliPhenolia® on Fat Oxidation

NCT07210099 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2026-03-31

No results posted yet for this study

Summary

There is current research interest in the use of fruit and plant-based food products containing high levels of natural antioxidants and their impact on exercise, which may be particularly beneficial for recreationally or low-active populations. One such product is an olive extract drink (called OliPhenolia®) produced by Fattoria La Vialla (an organic farm based in Northern Italy) and commercially available for the general public. Whilst previous research from the investigators (at Anglia Ruskin University) using this product has demonstrated potential antioxidant benefits and reduced oxygen cost during aerobic exercise, there are to date no studies investigating whether the short-term consumption of OliPhenolia® can benefit fat oxidation during exercise or whether such effects can be further enhanced employing a pre workout caffeinated beverage.

Therefore the aim of this study is two-fold:

i) to assess the impact of short-term supplementation (8 days) of OliPhenolia® relative to body mass on fat oxidation during aerobic cycling exercise in comparison to placebo in healthy recreationally active volunteers; and ii) whether potential benefits of OliPhenolia® on fat oxidation are enhanced with a pre-workout caffeinated beverage in comparison to placebo in healthy recreationally active volunteers.

Conditions

  • Healthy

Interventions

DIETARY_SUPPLEMENT

Concentrated olive fruit water

Supplementation of OliPhenolia twice daily for eight days. Dose equivalent to ≤1.0mg∙kg-1 of hydroxytyrosol.

DIETARY_SUPPLEMENT

Placebo

Placebo matched for taste and appearance consumed twice daily for eight days in the equivalent volume to the experimental product.

DIETARY_SUPPLEMENT

Anhydrous caffeine

A single bolus of flavoured water (150mL) containing 6mg/kg anhydrous caffeine taken as a pre-exercise beverage

DIETARY_SUPPLEMENT

Placebo beverage

A single bolus of flavoured water (150mL) containing 6mg/kg microcrystalline cellulose

Sponsors & Collaborators

  • Anglia Ruskin University

    lead OTHER

Principal Investigators

  • Justin D Roberts, Professor · Anglia Ruskin University

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-05-30
Primary Completion
2026-07-30
Completion
2026-09-30

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07210099 on ClinicalTrials.gov