Caffeine Kinetics and CrossFit®-Specific Performance

Summary

The study aims at assessing the relation between caffeine (CAF) and paraxanthine (PAX) kinetics after acute ingestion of caffeine (3 mg/kg body mass) in the form or mono- or multi-ingredient preparations and CrossFit®-specific performance or selected indicators of psychophysiological state. Blood indicators of muscle damage/recovery, acid-base balance and electrolytes levels will be evaluated. The impact of genetic variations in the polymorphisms rs5751876 in ADORA2A gene and rs762551 in CYP1A2 on CAF/PAX kinetics will be considered.

Conditions

• Supplementation
• Sports Nutrition
• Ergogenic Support
• Discipline-specific Performance

Interventions

DIETARY_SUPPLEMENT

CAFMONO supplementation

CAFMONO supplementation - random blind acute intake of in individual dose providing 3mg/kg BM of CAF. CAFMONO - Caffeine (anhydrous caffeine), Ostrovit Sp. z o.o., Zambrów, POLAND

DIETARY_SUPPLEMENT

CAFMIPS_1 supplementation

CAFMIPS\_1 supplementation - random blind acute intake of in individual dose providing 3mg/kg BM of CAF. CAFMIPS\_1 - Olimp Redweiler, Olimp Laboratories Sp. z o.o., Dębica, POLAND CAFMIPS\_1 - Olimp Redweiler, Olimp Laboratories Sp. z o.o., Dębica, POLAND

DIETARY_SUPPLEMENT

CAFMIPS_2 supplementation

CAFMIPS\_2 supplementation - random blind acute intake of in individual dose providing 3mg/kg BM of CAF. CAFMIPS\_2 - Muscle Clinic Furious, Noblepharma UG, BerlinVertrieb, GERMANY.

DIETARY_SUPPLEMENT

Placebo treatment

Placebo treatment - random blind acute intake of placebo preparation. Placebo will match the remaining test preparations with taste, colour and consistency, however it will be free of caffeine and any other substances possessing ergogenic potential.

Sponsors & Collaborators

• National Science Centre, Poland

  collaborator OTHER_GOV

• Poznan University of Life Sciences

  collaborator OTHER

• Poznan University of Physical Education

  lead OTHER

Principal Investigators

• Krzysztof Durkalec-Michalski, Prof., PhD · Department of Sports Dietetics, Poznan University of Physical Education

• Paulina M Nowaczyk, PhD · Department of Sports Dietetics, Poznan University of Physical Education

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

40 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-06-29

Primary Completion

2024-07-29

Completion

2024-07-30

Countries

• Poland

Study Locations