MedTrace Logo

Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

NCT07204652 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2026-02-11

No results posted yet for this study

Summary

The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease. The main question it aims to answer is:

Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease?

Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and movement problems, but by then the disease has already progressed significantly. Earlier detection could help doctors start treatment sooner.

Conditions

  • PARKINSON DISEASE (Disorder)
  • Parkinson
  • Parkinson's Disease and Parkinsonism
  • Parkinson Disease

Interventions

DIAGNOSTIC_TEST

No Intervention: Observational Cohort

No Intervention: Observational Cohort

Sponsors & Collaborators

  • Oregon Health and Science University

    collaborator OTHER

  • CND Life Sciences

    lead OTHER

Principal Investigators

  • Delaram Safarpour, MD, MSCE, FAAN · Oregon Health and Science University

Eligibility

Min Age
40 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-03
Primary Completion
2028-09-30
Completion
2029-09-30

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07204652 on ClinicalTrials.gov