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Establishing Alpha-synuclein RT-QuIC Assay as a Diagnostic Technique in REM Sleep Behaviour Disorder

NCT04266457 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2022-10-18

No results posted yet for this study

Summary

We hypothesise that a real-time quaking induced conversion assay for the detection of pathological alpha-synuclein (α -syn RTQuIC) can be used to differentiate between cases of idiopathic REM-sleep behaviour disorder (RBD) and RBD that is symptomatic of prodromal α-synucleinopathies.

Conditions

  • Sleep Disorder Rem Sleep Behavior
  • Parkinson's Disease, Lewy Body

Interventions

OTHER

No Intervention

No Intervention

Sponsors & Collaborators

  • Weston Brain Institute

    collaborator OTHER

  • University of Edinburgh

    lead OTHER

Principal Investigators

  • Renata L Riha, MD · University of Edinburgh

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2022-09-01
Completion
2022-09-01

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04266457 on ClinicalTrials.gov