A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors
NCT07182149 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 150
Last updated 2026-02-12
Summary
This study is being done to find out of NRM-823 is safe and can treat participants with locally advanced or metastatic solid tumors.
Conditions
- HNSCC
- ESCC
- Esophageal Adenocarcinoma
- Gastric Adenocarcinoma
- GEJ Adenocarcinoma
- Ovarian Cancer
- NSCLC
- Cervical Cancer
- Endometrial Cancer
- Triple Negative Breast Cancer (TNBC)
Interventions
- DRUG
-
NRM-823
NRM-823 is a bispecific T-Cell Engager
Sponsors & Collaborators
-
Normunity AccelCo, Inc.
lead INDUSTRY
Principal Investigators
-
Viviana Bozon, MD · Normunity AccelCo, Inc.
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-30
- Primary Completion
- 2027-05-30
- Completion
- 2028-10-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
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