A Study of RC108-ADC in Subjects With Advanced Malignant Solid Tumors
NCT04617314 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 67
Last updated 2026-01-06
Summary
This study will evaluate the safety, pharmacokinetics, and effect of RC108-ADC for injeciton in subjects with c-Met positive advanced malignant solid tumors.
Conditions
Interventions
- DRUG
-
RC108
RC108 for injection is a novel antibody-drug conjugate, with a c-Met-targeting antibody and a microtube inhibitor.
Sponsors & Collaborators
-
RemeGen Co., Ltd.
lead INDUSTRY
Principal Investigators
-
Yuankai Shi, M.D. · Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-03-10
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- China
Study Locations
More Related Trials
-
A Study of MHB048C in Patients With Advanced Solid Tumors
NCT07192120 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of MHB046C Injection in Patients With Advanced Solid Tumors
NCT06985355 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of DXC014 in Patients With Advanced Solid Tumors.
NCT07177937 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumours
NCT04914117 ·Status: COMPLETED ·Phase: PHASE1
-
JMT106 Injection in the Treatment of Advanced Solid Tumors
NCT07275073 ·Status: RECRUITING ·Phase: PHASE1
-
A Clinical Study of 9MW2821 in Subjects With Advanced Malignant Solid Tumors
NCT05216965 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
AMG 404 in Patients With Advanced Solid Tumors
NCT03853109 ·Status: COMPLETED ·Phase: PHASE1
-
Study of AMG 256 in Adult Subjects With Advanced Solid Tumors
NCT04362748 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Mitoxantrone Hydrochloride Liposome Injection Combination Therapy in Chinese Patients With Advanced Solid Tumors
NCT05344742 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study of AMG 337 in Subjects With Advanced Solid Tumors
NCT01253707 ·Status: COMPLETED ·Phase: PHASE1
-
Study of PHA-848125AC in Adult Patients With Advanced/Metastatic Solid Tumors
NCT01300468 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Injection HB0025 in Patients With Advanced Solid Tumors
NCT04678908 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase I Study of AL8326 in Advanced Solid Tumor
NCT04890587 ·Status: UNKNOWN ·Phase: PHASE1
-
A Phase Ia Clinical Study of QLF31907 Injection in Patients With Advanced Malignant Tumors
NCT05150405 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of SHR-A1909 in Subjects With Advanced Malignant Tumors
NCT05162469 ·Status: COMPLETED ·Phase: PHASE1
-
Study of ZG0895.HCl in Patients With Advanced Solid Tumors
NCT05877664 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of MHB009C in Patients With Advanced Solid Tumors
NCT07326488 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Clinical Study Evaluating H1710 for Injection in Participants With Advanced Solid Tumors
NCT06992713 ·Status: RECRUITING ·Phase: PHASE1
-
A Study of Mitoxantrone Hydrochloride Liposome Injection in Chinese Patients With Advanced Solid Tumors
NCT04921878 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Solid Tumor
NCT04719065 ·Status: UNKNOWN ·Phase: PHASE1
-
Clinical Study of BR105 Injection
NCT05351697 ·Status: TERMINATED ·Phase: PHASE1
-
3D011-08 Monotherapy in Subjects With Advanced Solid Tumors
NCT05099536 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of AMG 820 in Subjects With Advanced Solid Tumors
NCT01444404 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of HS-10386 in Participants With Advanced Solid Tumors
NCT05911464 ·Status: RECRUITING ·Phase: PHASE1
-
Study of the of the Safety and Tolerability of TT-00434 in Patients With Advanced Solid Tumors
NCT04830501 ·Status: COMPLETED ·Phase: PHASE1