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CTCA Prior to Invasive Angiography in Post-Bypass Patients (BYPASS CTCA 2)

NCT07165678 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 1000

Last updated 2026-03-02

No results posted yet for this study

Summary

The goal of this clinical trial is to evaluate whether a coronary computed tomography angiography (CTCA)-guided strategy can reduce the risk of death, heart attack, stroke, and hospital admissions in patients experiencing angina or myocardial infarction following coronary artery bypass graft (CABG) surgery. The main questions it aims to answer are:

* Can CTCA reduce major adverse cardiovascular events compared to standard invasive coronary angiography?
* Is CTCA a cost-effective and safer alternative that improves patient quality of life? Researchers will compare outcomes between patients receiving CTCA prior to angiography and those undergoing standard angiography alone to determine if CTCA improves clinical outcomes and procedural safety.

Participants will:

* Be randomly assigned to either CTCA-guided care or standard angiography
* Undergo coronary imaging and follow-up assessments
* Complete questionnaires on quality of life and healthcare resource use

Conditions

Interventions

DIAGNOSTIC_TEST

CTCA

Computed Tomography Cardiac angiography (CTCA) performed prior to invasive coronary angiogram (ICA).

Sponsors & Collaborators

  • National Institute for Health Research, United Kingdom

    collaborator OTHER_GOV

  • Queen Mary University of London

    lead OTHER

Principal Investigators

  • Daniel Jones, MRCP, PhD · Queen Mary University of London

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2026-09-30
Primary Completion
2027-09-30
Completion
2028-11-30

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07165678 on ClinicalTrials.gov