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Endometriosis-Angiopoietin-like Protein-4

NCT07164196 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 80

Last updated 2025-09-10

No results posted yet for this study

Summary

Endometriosis is a chronic inflammatory disease associated with pelvic pain, dyspareunia, and impaired ovarian reserve. Cancer antigen-125 (CA-125) is widely studied but limited by low specificity, while angiopoietin-like protein-4 (ANGPTL4) has emerged as a potential biomarker due to its role in angiogenesis and inflammation. In the current study it was aimed to investigate serum and peritoneal fluid ANGPTL4 levels in women with endometriosis compared to healthy controls, and to evaluate their associations with clinical symptoms, serum CA-125, and anti-Müllerian hormone levels.

Conditions

  • Endometriosis
  • Angiopoietin-like Protein-4
  • Pelvic Pain

Interventions

OTHER

Angiopoietin-like protein-4 (ANGPTL4) Peritoneal Fluid Level

Measurement of peritoneal fluid levels of Angiopoietin-like protein-4 (ANGPTL4) level by ELISA method.

OTHER

Cancer Antigen 125 (CA-125) Serum Level

Measurement of venous blood serum level of CA-125 level by ELISA method.

OTHER

Angiopoietin-like protein-4 (ANGPTL4) Serum Level

Measurement of venous blood serum level of Angiopoietin-like protein-4 (ANGPTL4) Level level by ELISA method.

Sponsors & Collaborators

  • Ankara City Hospital Bilkent

    lead OTHER

Principal Investigators

  • Merve Didem Eşkin Tanrıverdi, MD · Ankara City Hospital Bilkent

Eligibility

Min Age
18 Years
Max Age
44 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-06-05
Primary Completion
2025-08-21
Completion
2025-09-02

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07164196 on ClinicalTrials.gov