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Biomarkers in the Endometrial Fluid, Tissue, and Follicular Fluid of Moderate/Severe Endometriosis Patients

NCT07182643 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2025-09-19

No results posted yet for this study

Summary

This study aims to explore biomarkers in the endometrial fluid and tissue of women with moderate to severe endometriosis, with a specific focus on those involved in pre-receptive endometrium and embryo implantation. This research has the potential to uncover diagnostic indicators of impaired pre-receptive endometrium, examine pathophysiological pathways, and identify future targets for therapeutic intervention. Ultimately, the findings may contribute to more personalized fertility treatments, offering new hope for women struggling with endometriosis-related infertility.

Conditions

  • Endometriosis

Interventions

DIAGNOSTIC_TEST

Endometrial fluid

Endometrial fluid collection in the day of OPU

DIAGNOSTIC_TEST

Endometrial biopsy

Endometrial biopsy on the OPU day, Pipelle

DIAGNOSTIC_TEST

Follicular fluid

Follicular fluid sampling on the OPU day

Sponsors & Collaborators

  • Region Stockholm

    lead OTHER_GOV

Principal Investigators

  • Kenny Rodriguez-Wallberg, Professor · Onk/Pat Karolinska Institute

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-10-01
Primary Completion
2027-12-31
Completion
2027-12-31

Countries

  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07182643 on ClinicalTrials.gov