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Genicular Nerve Block for Knee Pain in the ED

NCT07158736 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2026-02-12

No results posted yet for this study

Summary

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Conditions

  • Knee Pain

Interventions

PROCEDURE

Genicular nerve block with bupivacaine and corticosteroids

genicular nerve block with ideal body-weight dosing of bupivacaine 0.5% with 4 mg dexamethasone

OTHER

Standard of Care

This involves standard of care pain relief for patients who do not receive the genicular nerve block for knee pain, such as acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids.

Sponsors & Collaborators

Principal Investigators

  • Michael M Shalaby, MD · University of Pennsylvania

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-08-06
Primary Completion
2026-08-01
Completion
2026-09-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07158736 on ClinicalTrials.gov