Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau
NCT06639503 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 38
Last updated 2026-02-05
Summary
The investigators are conducting this research study to find better ways of treating pain following knee surgery. There is a standard (accepted) approach, which involves injection of numbing medication into the area around the participant surgical incision. The investigators hope to discover if providing numbing medication to a nerve that controls pain in a larger area of the knee (a nerve block), might be better at post-operative pain control.
Conditions
- Tibial Plateau Fractures
Interventions
- DRUG
-
Bupivacain
5mL 0.25% bupivacain
Sponsors & Collaborators
-
University of Chicago
lead OTHER
Principal Investigators
-
Anthony Christiano, MD · University of Chicago
Study Design
- Allocation
- RANDOMIZED
- Purpose
- SUPPORTIVE_CARE
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-11-01
- Primary Completion
- 2026-09-01
- Completion
- 2026-10-14
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?
NCT03326999 ·Status: COMPLETED ·Phase: PHASE4
-
US Guided GNB vs Saline Injection for TKA
NCT03316118 ·Status: TERMINATED ·Phase: PHASE4
-
Obturator Nerve Block With Femoral and Sciatic Block
NCT01409460 ·Status: COMPLETED ·Phase: NA
-
Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
NCT02121392 ·Status: COMPLETED ·Phase: NA
-
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
NCT06004882 ·Status: RECRUITING ·Phase: NA
-
Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
NCT01279447 ·Status: COMPLETED ·Phase: PHASE4
-
Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty
NCT01759277 ·Status: COMPLETED ·Phase: PHASE4
-
Persistent Post Surgical Pain After Total Knee Arthroplasty
NCT06182059 ·Status: RECRUITING ·Phase: NA
-
Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty
NCT02713178 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
NCT00677261 ·Status: COMPLETED ·Phase: NA
-
Study to Evaluate ACB Versus FNB Early Postoperative Period Functional Outcomes After TKA
NCT02218814 ·Status: COMPLETED ·Phase: NA
-
Motor-Sparing Femoral Nerve Block Dose
NCT02909257 ·Status: TERMINATED ·Phase: PHASE4
-
Evaluation of Optimal Dose of Local Anesthetics for Patient Controlled Continuous Femoral Nerve Block
NCT01198340 ·Status: UNKNOWN ·Phase: NA
-
Continuous Femoral Nerve Blockade and Readiness to Discharge Following Total Knee Arthroplasty
NCT00803348 ·Status: COMPLETED ·Phase: NA
-
Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
NCT01966263 ·Status: COMPLETED ·Phase: PHASE4
-
Knee Arthroscopy for Pain Control
NCT06701175 ·Status: WITHDRAWN ·Phase: NA
-
Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
NCT02453321 ·Status: COMPLETED ·Phase: PHASE4
-
Genicular Nerve Block for Knee Pain in the ED
NCT07158736 ·Status: RECRUITING ·Phase: NA
-
Saphenous Nerve Block After Tibial Plateau ORIF
NCT04314570 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Anterior Femoral and Adductor Canal Nerve Blocks in Peds Knees
NCT06590402 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Bupivacaine Liposomes or Bupivacaine for Femoral Triangle or Adductor Block on Analgesia After Total Knee Replacement
NCT06653621 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial
NCT02773537 ·Status: COMPLETED ·Phase: NA
-
Genicular vs IPACK Block for Analgesia in Knee Arthroplasty
NCT07171931 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Addition of Popliteal Plexus Block to Continuous Femoral Nerve Block for Total Knee Arthroplasty
NCT04048889 ·Status: UNKNOWN ·Phase: NA
-
The Effect of Femoral Nerve Block on Postoperative Opioid Use After Anterior Cruciate Ligament (ACL) Reconstruction
NCT00175630 ·Status: UNKNOWN ·Phase: PHASE1