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Cardiac Amyloid Deposits and Heart Dysfunction in Alzheimer's Disease

NCT07154394 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2025-09-04

No results posted yet for this study

Summary

This study seeks to explore the possible common pathogenesis of both cardiac amyloidosis and Alzheimer's disease, which can both be associated with amyloid deposits. Using Positron Emission Tomography (PET) scans with amyloid tracers - a conventional tool for non-invasively imaging amyloid deposits in Alzheimer's disease - the research will extend this imaging methodology to the heart.

The study will conduct additional PET/MRI scans of the heart in patients undergoing amyloid tracer PET scans for Alzheimer's evaluations. Each participant will also undergo an echocardiogram and a clinical examination of dementia.

This could potentially enhance diagnostic practices in both cardiac amyloidosis and Alzheimer's disease.

Conditions

Sponsors & Collaborators

  • University Hospital, Essen

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-15
Primary Completion
2023-08-14
Completion
2025-09-14

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07154394 on ClinicalTrials.gov