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Contribution of Computed Tomography and Cardiac-MRI in Atrial Fibrillation Ablation

NCT04281329 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 130

Last updated 2025-05-06

No results posted yet for this study

Summary

Atrial fibrillation ablation (AF) is a standard interventional treatment for patients with symptomatic AF refractory to medical treatment. The known predictive factors for the success of the procedure remain insufficient to predict the probabilities of success and to appropriately select the patients who could benefit the most from this procedure. Left atrium imaging by MRI or CT may be able to identify AF substrate. However data are lacking about the practical impact of these techniques in routine practice to predict AF ablation outcome.

The "CT-AF" study is a prospective, interventional, multicenter cohort study. The main objective of this study is to evaluate the prognostic value of a new automated measurement technique for intra-myocardial atrial fat measurement in cardiac CT and the measurement of global left atrial strain in MRI in patients who are candidates for first AF ablation.

The main outcome will be the relationship between the relative volume of left atrial fat measured with CT and total left atrial strain in MRI and recurrence of AF at 1 year after the ablation procedure (blanking period of 3 months post ablation excluded).

Conditions

Interventions

PROCEDURE

Magnetic resonance imaging

Cardiac magnetic resonnance imaging before catheter ablation.

Sponsors & Collaborators

  • University Hospital, Bordeaux

    collaborator OTHER

  • Centre Cardiologique du Nord

    collaborator OTHER

  • Assistance Publique - Hôpitaux de Paris

    lead OTHER

Principal Investigators

  • Alban REDEHEUIL, MD, PhD · Centre Hospitalier Universitaire Pitié-Salpêtrière Paris

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2026-04-01
Completion
2026-11-01

Countries

  • France

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04281329 on ClinicalTrials.gov