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Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury

NCT07134244 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 105

Last updated 2025-08-21

No results posted yet for this study

Summary

Knee osteoarthritis is a complex condition, and selecting effective non-drug treatments like orthoses or exercise is often difficult and imprecise. This study will follow individuals with early-stage knee osteoarthritis or previous anterior cruciate ligament injury to develop computational models that predict cartilage degeneration and pain over time. The models will integrate data from medical imaging, movement analysis, muscle strength testing, pain assessments, questionnaires, and biomarkers to improve personalized treatment planning.

Conditions

  • Osteoarthritis, Knee
  • Anterior Cruciate Ligament Injuries

Sponsors & Collaborators

  • Lund University

    collaborator OTHER

  • University of Eastern Finland

    collaborator OTHER

  • Aalborg University Hospital

    collaborator OTHER

  • Aalborg University

    lead OTHER

Principal Investigators

  • Michal Skipper Andersen, Phd · Department of Materials and Production, Aalborg University, Denmark

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-26
Primary Completion
2035-09-26
Completion
2036-09-26

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07134244 on ClinicalTrials.gov