Caffeine Mouth Rinsing at Different Doses in Female Team-Sport Athletes: A Randomized, Double-Blind, Placebo-Controlled Trial

Summary

Objective:

To evaluate the effects of different caffeine mouth rinse concentrations (1%, 2%, and 3%) on Running Anaerobic Sprint Test (RAST) performance in female team-sport athletes.

Main Questions:

1. Do caffeine mouth rinses improve RAST performance in female team-sport athletes?
2. Do different caffeine mouth rinse concentrations affect ratings of perceived exertion (RPE)?

Method:

Thirteen trained female football and handball players (23.0 ± 4.5 years) completed four randomized, double-blind, crossover conditions (1%, 2%, and 3% caffeine mouth rinses, and placebo). Each trial involved six 35 m sprints separated by 10 s of rest. RPE was recorded immediately after each session.

Conditions

• Dietary Supplement
• Sports Performance

Interventions

DIETARY_SUPPLEMENT

Placebo: Mouth rinse with plain water

Placebo: Mouth rinse with plain water, containing no caffeine, serving as the control condition.

DIETARY_SUPPLEMENT

Experimental: Low mouth rinse caffeine concentration (1%)

Arm Description: Low caffeine concentration: Mouth rinse containing 1% caffeine solution (based on weight/volume).

DIETARY_SUPPLEMENT

Moderate caffeine concentration (2% caffeine solution weight/volume).

Moderate caffeine concentration: Mouth rinse containing 2% caffeine solution (weight/volume).

DIETARY_SUPPLEMENT

High caffeine concentration (3% caffeine solution weight/volume).

High caffeine concentration: Mouth rinse containing 3% caffeine solution (weight/volume).

Sponsors & Collaborators

• Eastern Mediterranean University

  collaborator OTHER

• Northumbria University

  collaborator OTHER

• Universidad Francisco de Vitoria

  collaborator OTHER

• Ankara University

  collaborator OTHER

• Universidad Pontificia Comillas

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

CROSSOVER

Eligibility

Min Age

18 Years

Max Age

35 Years

Sex

FEMALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-09-24

Primary Completion

2024-12-01

Completion

2024-12-22

Countries

• Turkey (Türkiye)

Study Locations