Stepwise Strategy for Treatment of Atrialfibrillation Substrate Study
NCT07129564 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 480
Last updated 2025-08-19
Summary
Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesized that radiofrequency ablation surgery for atrial fibrillation has a higher success rate and a lower recurrence rate of atrial fibrillation in patients with improved atrial stroma. This study is a multicenter, prospective, observational study conducted in China to evaluate whether sacubitril/valsartan can reduce atrial fibrillation recurrence rates, improve cardiac structure and function, and analyze the factors influencing the maintenance rate of sinus rhythm after atrial fibrillation ablation.
Conditions
Interventions
- OTHER
-
treatment react
Reverse remodeling of the LA was defined as at least a 15% reduction in the max LA volume after electrical or pharmacological cardioversion for 3 months
Sponsors & Collaborators
-
Yuehui Yin
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-04-27
- Primary Completion
- 2024-11-25
- Completion
- 2026-07-01
Countries
- China
Study Locations
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