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Atrial Fibrillation With Sinus Node Dysfunction: Intensive Device Follow-up

NCT03607123 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2018-07-31

No results posted yet for this study

Summary

The study will try to access the efficacy of atrial pacing, medication and radiofrequency ablation in treating patients with paroxysmal atrial fibrillation and sinus node dysfunction; to identify the response to these treatments in patients with "functional" and organic sinus node dysfunction respectively; to explore the necessity of pacemaker implantation in patients with "functional" sinus node dysfunction. Patients who meet the inclusion criteria will receive pacemaker implantation followed by trial pacing, medication and radiofrequency ablation of AF. Device data will be analyzed to answer the question. And after follow-up of 1 year, lower rate of pacemaker will be set as 40 bpm for patients without AF. The proportion of pacing and patients' tolerance will be analyzed.

Conditions

Interventions

OTHER

programing of pacemaker

Different programing parameters will be set in different group/stage

PROCEDURE

AF ablation

AF ablation can only be performed in Step 3

DRUG

Anti arryhthmic drugs

Anti arryhthmic drugs can be prescribed in Step 2, Step3 and SAFE PAF-SND

Sponsors & Collaborators

  • Zhejiang University

    collaborator OTHER

  • The First Affiliated Hospital with Nanjing Medical University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-07-04
Primary Completion
2022-07-04
Completion
2022-07-04

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03607123 on ClinicalTrials.gov