Postoperative Euglycemic Ketoacidosis Frequency in Sodium-Glucose Cotransporter-2 Inhibitor Users
NCT07127406 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2025-09-17
Summary
The goal of this observational study is to determine the frequency of postoperative euglycemic diabetic ketoacidosis (EDKA) in patients receiving Sodium- Glucose Cotransporter-2 (SGLT-2) inhibitors. The main questions it aims to answer are:Is the use of SGLT-2 inhibitors a factor that increases the incidence of euglycemic diabetic ketoacidosis in patients in the perioperative period or what conditions in the perioperative period cause EDKA in patients on SGLT-2 inhibitors?
Conditions
- Diabetic Ketoacidosis
- Postoperative Care
Sponsors & Collaborators
-
Kocaeli City Hospital
lead OTHER_GOV
Principal Investigators
-
Ayşe Z Turan Cıvraz, Assoc. Prof. · Kocaeli City Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2025-05-01
- Primary Completion
- 2027-06-01
- Completion
- 2027-06-01
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Strict or Liberal Insulin Protocol Following Coronary Artery Bypass Graft (CABG) Surgery
NCT01033916 ·Status: COMPLETED ·Phase: NA
-
Prevention and Treatment of Common Hyperglycemia in Surgery Pilot
NCT06624956 ·Status: COMPLETED ·Phase: PHASE4
-
Insulin Degludec vs Insulin Glargine for Glycemic Control in Critical Illness Hyperglycemia
NCT06178874 ·Status: COMPLETED ·Phase: NA
-
Intensive Insulin Therapy in Patients Undergoing Coronary Artery Bypass Surgery
NCT01361594 ·Status: COMPLETED ·Phase: PHASE3
-
Treatment With SGLT-2 Inhibitor for Postoperative Hyperglycemia in Acute Abdominal Surgery - a Randomized Trial
NCT05314725 ·Status: UNKNOWN ·Phase: PHASE2
-
Intravenous Bolus-infusion Versus Sliding Scale of Insulin for Intra-operative Glycemic Control
NCT05136157 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Children with Diabetic Ketoacidosis
NCT06599203 ·Status: NOT_YET_RECRUITING
-
Glucose-insulin-potassium Therapy Improves Lactic Acidosis in Liver Transplantation
NCT03522181 ·Status: COMPLETED ·Phase: NA
-
Outcomes With Tight Control of Hyperglycemia in Cardiac Surgery Patients
NCT00282698 ·Status: COMPLETED ·Phase: PHASE3
-
Outcomes Study of Hyperinsulinemic Glucose Control in Cardiac Surgery
NCT00524472 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of a Glargine-based Hospital Discharge Algorithm in Coronary Artery Bypass Graft (CABG) Patients
NCT01792830 ·Status: COMPLETED ·Phase: PHASE3
-
Comparing Blood Glucose Control Intraoperative Between Insulin Drip vs. Insulin Boluses Will Provide Valuable Information on the Optimal Method for Achieving Blood Glucose Control Intraoperatively.
NCT07056088 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Glycemic Control and Surgical Site Infection Incidence Among Liver Transplantation Recipients
NCT03474666 ·Status: TERMINATED ·Phase: NA
-
Adherence, Efficacy and Safety of an Insulin Protocol in the Critically Ill: A Prospective Observational Study
NCT00288743 ·Status: COMPLETED ·Phase: PHASE2
-
Improving Outcomes In Diabetic Patients During CABG Surgery By Optimizing Glycemic Control
NCT00460499 ·Status: COMPLETED ·Phase: PHASE1
-
Outcome of Glargine Insulin in Renal Impairment Patients With Diabetic Ketoacidosis
NCT05219942 ·Status: UNKNOWN ·Phase: NA
-
Comparing Efficacy Between Two Protocols of Intravenous Insulin Infusion for Diabetic Adults in ICU
NCT06810596 ·Status: RECRUITING ·Phase: NA
-
Early Subcutaneous Insulin Glargine Plus Standard of Care for Treatment of Diabetic Ketoacidosis
NCT02930044 ·Status: COMPLETED ·Phase: NA
-
Degludec Insulin Use in Critically Ill Patients
NCT06056167 ·Status: COMPLETED ·Phase: NA
-
Effectiveness of Subcutaneous Glargine On The Time To Closure of The Anion Gap in Patients Presenting to the Emergency Department With Diabetic Keto-acidosis
NCT02006342 ·Status: COMPLETED ·Phase: NA
-
The Efficacy of Glucagon Like Peptide (GLP) - 1(7-36) Amide for Glycemic Control in Critically Ill Patients
NCT00798590 ·Status: TERMINATED ·Phase: PHASE2
-
Intermittent vs Continuous Enteral Nutrition in Glycaemic Control of Diabetic ICU Patients
NCT07054476 ·Status: COMPLETED ·Phase: NA
-
SGLT2 Inhibitors and Perioperative Period
NCT06326528 ·Status: NOT_YET_RECRUITING
-
The Effects of SGC on Glucose Control in Critically Ill Patients With Sepsis
NCT02980588 ·Status: UNKNOWN ·Phase: NA
-
Perioperative Stress Hyperglycemia in General and Vascular Surgery Patients
NCT04862234 ·Status: TERMINATED ·Phase: PHASE4