Glucose-insulin-potassium Therapy Improves Lactic Acidosis in Liver Transplantation
NCT03522181 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80
Last updated 2018-05-11
Summary
Lactic acidosis is a common phenomenon occurring during orthotopic liver transplantation (OLT), especially during the anhepatic and early postreperfusion phases. However, little drugs effectively decrease the degree of lactic acidosis when it happens. The aim of this study is to explore whether glucose-Insulin-Potassium(GIK) infusion can relieve metabolic acidosis and improve perioperative outcome in patients undergoing OLT.
Conditions
- Liver Transplantation
Interventions
- OTHER
-
saline
saline
- OTHER
-
Insulin
Sponsors & Collaborators
-
Central South University
lead OTHER
Principal Investigators
-
Ru-Ping Dai, MD · Second Xiangya Hospital of Central South University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-02-29
- Primary Completion
- 2017-10-31
- Completion
- 2017-11-30
Countries
- China
Study Locations
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