Pre-eclampsia and Biochemical Markers
NCT02665897 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2017-06-09
Summary
In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney impairment characteristics, a recent study demonstrated that the serum levels of NGAL increased at the end of the second trimester in women who subsequently developed pre-eclampsia compared to the control group.
This correlates well with the endothelial damage that occurs during pre-eclampsia and thus NGAL can be considered as a promising marker in predicting both early and late onset pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the precision, and sensitivity for detection of risk and reliability of using biomarkers for pre-eclampsia.
Conditions
- Detection of Preeclampsia Complications
Sponsors & Collaborators
-
Assiut University
lead OTHER
Eligibility
- Min Age
- 20 Years
- Max Age
- 40 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2016-12-31
- Completion
- 2017-05-31
Countries
- Egypt
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