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Integrating HIV Prevention With TB Household Contact Evaluation in Uganda

NCT07119359 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 2480

Last updated 2026-05-05

No results posted yet for this study

Summary

This household randomized implementation study assesses the implementation and effectiveness of home-based HIV self- testing and PrEP initiation versus standard clinic referral for PrEP initiation during modified standard-of-care (modified SOC) household TB contact investigation in Uganda. It uses qualitative methods to evaluate the process of implementing the intervention and a health economic evaluation to assess the financial sustainability of this strategy.

Conditions

  • Tuberculosis (TB)
  • Human Immunodeficiency Virus (HIV) Prophylaxis

Interventions

OTHER

Home-based HIV self-testing

Integration of HIV self-testing into TB household contact investigation

OTHER

Home-based initiation of PrEP

Integration of PrEP initiation into TB household contact investigation

Sponsors & Collaborators

  • Infectious Diseases Institute, Uganda

    collaborator OTHER

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • University of Washington

    lead OTHER

Principal Investigators

  • Jennifer M Ross, MD, MPH · University of Washington

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
15 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-12-10
Primary Completion
2029-08-01
Completion
2029-08-31

Countries

  • Uganda

Study Locations

More Related Trials

Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07119359 on ClinicalTrials.gov